Diethyl Ether Used In Anesthesia

2 can be used as sole agent for anesthesia as it has all properties of anesthesia viz narcosis analgesia muscle relaxation or in other words it is the only complete anesthetic agent.

Diethyl ether used in anesthesia. It was first used by an american doctor in 1842. However ether trichloroethylene are still in use in some developing countries. Ether anesthesia is considered the first form of anesthesia and thus represents the birth of anesthesia.

Diethyl ether is a volatile anesthetic that was used to induce general anesthesia. For treatment with diethyl ether rats were put in a closed 9 4 jar containing 3 paper towels saturated with 40 ml of diethyl ether. In fact all commonly used inhalational agents sevoflurane desflurane and isoflurane are halogenated ether compounds which is to say they possess the c o c.

Its minimum alveolar concentration mac is 2 0 in humans and its blood gas partition coefficient is 12. Diethyl ether was the first truly successful general anaesthetic agent for several reasons. It s easy and cheap to make from ordinary alcohol.

It was sometimes called ethyl ether or simply ether. Any high street chemist in the 19th century could do it. Ether also known as diethyl ether is a colourless chemical compound that is gaseous at room temperature.

Ether was sometimes used in place of chloroform because it had a higher therapeutic index a larger difference between the recommended dosage and a toxic overdose. Diethyl ether or simply ether is an organic compound in the ether class with the formula c 2 h 5 2 o sometimes abbreviated as et 2 o see pseudoelement symbols it is a colorless highly volatile sweet smelling ethereal odour flammable liquid it is commonly used as a solvent in laboratories and as a starting fluid for some engines. The same procedure was used for treatment with isoflurane and the animals were kept inside the closed jars until loss of righting reflex average exposure time was 75 s for both treatments.

Ether is still very rarely used in many developing countries like india. It has a boiling point bp of 35 c vapour pressure vp 442 blood gas coefficient 15 2 oil gas coefficient 50 2 mac 2 5 50 metabolism flammable and ignites at 154 c decomposed by air light and heat it is metabolized to ethanol acetaldehyde. 3 thus the concentrations reached in the blood may be 24 or higher if ether is used for general anesthesia.